CIRUGIA ESTEREOTAXICA PDF

Download/Embed scientific diagram | Implantación de los electrodos mediante cirugía estereotáxica from publication: [Measurement of acetylcholine and sleep . La radio cirugía estereotaxica (por media del bisturí de rayos gamma) normalmente no es una opción reconocida para tratar los angiomas cavernosos del. Congreso bianual de la ASSFN – Sociedad Americana de Neurocirugía Funcional y Estereotáxica. Del 21 de Mayo al 3 de junio de , se celebrará en.

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Stereotactic surgery is used to place electrodes or cannulas in the brain in order to study the function of several brain structures in preclinical research. The hippocampus has been extensively studied with this methodology due to its involvement in a wide range of neurological, cognitive, emotional, and affective disorders.

However, the effects of stereotactic surgery on coordination and motor activity should be evaluated in order to determine whether this surgical procedure causes any neurological alterations that may bias the results of studies incorporating this technique. We evaluated the effects of stereotactic surgery and implantation of a cannula into the hippocampus of female Wistar rats on the motor activity, forced swim, and rotarod tests.

The stage of the oestrous cycle was included in the statistical analysis. Stereotactic surgery had no impact on any of the motor activity variables assessed in the open field squares crossed, time spent in grooming, and rearingforced swim turning behaviour, lateral swimming, latency to first immobility, and time spent immobileand rotarod latency to fall tests, compared with intact rats. Regardless of surgical manipulation, rats in the metestrus and diestrus stages crossed a greater number of squares and displayed longer immobility times than those in the proestrus and estrus stages.

Stereotactic surgery for cannula placement in the dorsal hippocampus does not affect coordination and motor activity in rats. We can therefore conclude that this procedure has no neurological complications that may interfere in the interpretation of results of studies applying this technique. Se incluyeron a 56 ratas hembras Wistar de 3 meses de cirhgia, con un peso entre g al inicio de los experimentos. El acceso al agua y alimento fue ad libitum.

Antes de iniciar las pruebas conductuales, se obtuvieron diariamente frotis vaginales de cada rata. En un primer experimento, se formaron aleatoriamente 2 grupos de ratas: Las ratas de ambos esgereotaxica fueron evaluadas en las pruebas de actividad locomotora y nado. En un segundo experimento, se incluyeron otros 2 grupos: Pasado este tiempo, las ratas fueron evaluadas en las pruebas conductuales. En esta prueba se evaluaron: Todas las sesiones de prueba fueron videograbadas.

Tiempo total de inmovilidad en la prueba de nado. Por su parte, el acicalamiento es considerado como un indicador del cirugja motivacional y emocional de la rata. Las diferencias que se encontraron en el tiempo total de inmovilidad estuvieron relacionadas solo con la fase del ciclo estral.

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Tampoco se detectaron diferencias asociadas con la fase del ciclo estral. Los autores declaran no tener conflicto de intereses. Read this article in English. Analysis of activity and motor coordination in rats undergoing stereotactic surgery and implantation of a cannula extereotaxica the dorsal hippocampus.

Under a Creative Commons license. Introduction Stereotactic surgery is used to place electrodes or cannulas in the brain in order to study the function of several brain structures in preclinical research. However, the effects of stereotactic surgery on coordination and motor activity should be evaluated in order to determine whether this surgical procedure causes any neurological alterations that may bias the results of studies incorporating this technique.

Methods We evaluated the effects of stereotactic surgery and esterfotaxica of a cannula into the hippocampus of female Wistar rats on the motor activity, forced swim, and rotarod tests.

The stage of the oestrous cycle was included in the statistical cirigia. Results Stereotactic surgery had no impact on any of the motor activity variables assessed in the open field squares esgereotaxica, time spent in grooming, and rearingforced swim turning behaviour, lateral swimming, estereptaxica to first immobility, and time spent immobileand rotarod latency to fall tests, compared with intact estereotaxcia. Regardless of surgical manipulation, rats in the metestrus and diestrus stages crossed a greater number of squares and displayed longer immobility times than those in the proestrus and estrus stages.

Conclusion Stereotactic surgery for cannula placement in the dorsal hippocampus does not affect coordination and motor activity in rats. We can therefore conclude that this procedure has no neurological complications that may interfere in the interpretation of results of studies applying eetereotaxica technique.

Frotis vaginal Antes de iniciar las pruebas conductuales, se obtuvieron diariamente frotis vaginales de cada rata. Grupos experimentales En un primer experimento, se formaron aleatoriamente 2 grupos de ratas: Pasado este tiempo, las ratas fueron evaluadas en las pruebas conductuales.

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